Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome.

BMC genomics - 30 Oct 2012

Gao Chuan, Devarajan Karthik, Zhou Yan, Slater Carolyn M, Daly Mary B, Chen Xiaowei

Abstract excerpt

BACKGROUND: The significant mortality associated with breast cancer (BCa) suggests a need to improve current research strategies to identify new genes that predispose women to breast cancer. Differential allele-specific expression (DASE) has been shown to contribute to phenotypic variables in humans and recently to the pathogenesis of cancer. We previously reported that nonsense-mediated mRNA decay (NMD) could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcium-Binding Proteins

Share to Epithelial Cells

Share to Mammary Glands, Human

Share to Nonsense Mediated mRNA Decay

Share to Primary Cell Culture

Share to Ubiquitin Thiolesterase

Source

Open in PubMed Open full text

Identifiers

PMID: 23107584
DOI: 10.1186/1471-2164-13-570
PMCID: PMC3532379

Genes

DMBT1
BRCA1
USP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome.PMID 23107584Read ↗

Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated by Cis Noncoding Mutations.Semantic proximity Read ↗

Identification of candidate causal variants and target genes at 41 breast cancer risk loci through differential allelic expression analysis.Semantic proximity Read ↗

Differential Allele-Specific Expression Uncovers Breast Cancer Genes Dysregulated By <i>Cis</i> Noncoding MutationsSemantic proximity Read ↗

Variable expression quantitative trait loci analysis of breast cancer risk variants.Semantic proximity Read ↗

Variable expression quantitative trait loci analysis of breast cancer risk variantsSemantic proximity Read ↗

Mapping of cis-regulatory variants by differential allelic expression analysis identifies candidate causal variants and target genes of 41 breast cancer risk lociSemantic proximity Read ↗

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.Semantic proximity Read ↗

Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.Semantic proximity Read ↗

Extent of differential allelic expression of candidate breast cancer genes is similar in blood and breast.Semantic proximity Read ↗

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.Semantic proximity Read ↗

Allele-specific expression: applications in cancer and technical considerations.Semantic proximity Read ↗

A Comprehensive cis-eQTL Analysis Revealed Target Genes in Breast Cancer Susceptibility Loci Identified in Genome-wide Association Studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.