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Article

Conditional knockout of the Slc5a6 gene in mouse intestine impairs biotin absorption.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jan 2013

Ghosal Abhisek, Lambrecht Nils, Subramanya Sandeep B, Kapadia Rubina, Said Hamid M

Abstract excerpt

The Slc5a6 gene expresses a plasma membrane protein involved in the transport of the water-soluble vitamin biotin; the transporter is commonly referred to as the sodium-dependent multivitamin transporter (SMVT) because it also transports pantothenic acid and lipoic acid. The relative contribution of the SMVT system toward carrier-mediated biotin uptake in the native intestine in vivo has not been established. We...

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Identifiers

PMID: 23104561
DOI: 10.1152/ajpgi.00379.2012
PMCID: PMC3543636

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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