Article
Cys(294) is essential for the function of the human sodium-dependent multivitamin transporter.
Biochimica et biophysica acta - 1 Jan 2012
Ghosal Abhisek, Said Hamid M
Abstract excerpt
The sodium-dependent multivitamin transporter (SMVT) plays an important role in biotin uptake in the intestine and other cell types. While significant knowledge has been gained with regard to regulation and cell biology of the SMVT system, there is little known about its structure-function relationships. Here we examined the role of each of the ten conserved (among species) cysteine residues in the function of...
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