Article
Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.
Neuroreport - 5 Dec 2012
Drummond Jana B, Simmons Micah, Haroutunian Vahram, Meador-Woodruff James H
Abstract excerpt
Schizophrenia has been proposed to be associated with abnormal glutamatergic neurotransmission. The AMPA subtype of glutamate receptors (AMPARs) mediates fast excitatory synaptic transmission in the brain, and their trafficking and function is regulated in part by AMPAR auxiliary proteins including the cornichons (CNIH) and transmembrane AMPAR-regulatory proteins. Abnormal regulation of AMPARs through altered...
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