Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of an MHC class I ligand for the single member of a killer cell lectin-like receptor family, KLRH1.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2012

Daws Michael R, Dai Ke-Zheng, Zinöcker Severin, Naper Christian, Kveberg Lise, Hedrich Hans J, Rolstad Bent, Vaage John T

Abstract excerpt

Natural killer cells are able to recognize and kill target cells according to differences in MHC class I expression. In rodents, the Ly49 receptors are primarily responsible for this MHC differentiation. We previously described the cloning of a novel C-type lectin-like receptor, KLRH1, encoded in the NK complex adjacent to the Ly49 genes and expressed by subsets of NK and NKT cells. MHC influence on selection of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CHO Cells
Share to Cricetinae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Reporter

Share to Histocompatibility Antigens

Share to Killer Cells, Natural

Share to Ligands

Share to Protein Isoforms

Share to Receptors, Immunologic

Source

Identifiers

PMID: 23100519
DOI: 10.4049/jimmunol.1201983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of an MHC class I ligand for the single member of a killer cell lectin-like receptor family, KLRH1.PMID 23100519Read ↗

Ly49 receptors: evolution, genetic diversity, and impact on immunity.Semantic proximity Read ↗

The NK2.1 receptor is encoded by Ly-49C and its expression is regulated by MHC class I alleles.Semantic proximity Read ↗

Ly-49 receptors and their functions.Semantic proximity Read ↗

Class I MHC-binding characteristics of the 129/J Ly49 repertoire.Semantic proximity Read ↗

Genes in two major histocompatibility complex class I regions control selection, phenotype, and function of a rat Ly-49 natural killer cell subset.Semantic proximity Read ↗

Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination.Semantic proximity Read ↗

H-2 allele specificity of the NK cell C-type lectin-like MHC class I receptor Ly49A visualized by soluble Ly49A tetramer.Semantic proximity Read ↗

Natural killer cell receptors in cattle: a bovine killer cell immunoglobulin-like receptor multigene family contains members with divergent signaling motifs.Semantic proximity Read ↗

Mouse Nkrp1-Clr gene cluster sequence and expression analyses reveal conservation of tissue-specific MHC-independent immunosurveillance.Semantic proximity Read ↗

Evolution of the Ly49 and Nkrp1 recognition systems.Semantic proximity Read ↗

Natural killer cell subsets in man and rodents.Semantic proximity Read ↗

The evolution of natural killer cell receptors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.