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Article

Pleomorphic Xanthoastrocytoma: Natural History and Long-Term Follow-Up.

Brain pathology (Zurich, Switzerland) - 1 Sept 2015

Ida Cristiane M, Rodriguez Fausto J, Burger Peter C, Caron Alissa A, Jenkins Sarah M, Spears Grant M, Aranguren Dawn L, Lachance Daniel H, Giannini Caterina

Abstract excerpt

Prognostic significance of histological anaplasia and BRAF V600E mutation were retrospectively evaluated in 74 patients with pleomorphic xanthoastrocytoma (PXA). Median age at diagnosis was 21.5 years (31 pediatric, 43 adult) and median follow-up 7.6 years. Anaplasia (PXA-AF), defined as mitotic...

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Source

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Identifiers

PMID: 25318587
DOI: 10.1111/bpa.12217
PMCID: PMC4400218

Genes

BRAF
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25318587-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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