Article
Imputation reliability on DNA biallelic markers for drug metabolism studies.
BMC bioinformatics - 1 Jan 2012
Mijatovic Vladan, Iacobucci Ilaria, Sazzini Marco, Xumerle Luciano, Mori Antonio, Pignatti Pier Franco, Martinelli Giovanni, Malerba Giovanni
Abstract excerpt
BACKGROUND: Imputation is a statistical process used to predict genotypes of loci not directly assayed in a sample of individuals. Our goal is to measure the performance of imputation in predicting the genotype of the best known gene polymorphisms involved in drug metabolism using a common SNP array genotyping platform generally exploited in genome wide association studies. METHODS: Thirty-nine (39) individuals...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.