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Article

Analysis of possible mechanisms accounting for raf-1 kinase inhibitor protein downregulation in hepatocellular carcinoma.

Omics : a journal of integrative biology - 1 Nov 2012

Poma Paola, Labbozzetta Manuela, Vivona Nicoletta, Porcasi Rossana, D'Alessandro Natale, Notarbartolo Monica

Abstract excerpt

Abstract Raf-1 kinase inhibitor protein (RKIP) is a tumor and metastasis suppressor that promotes drug-induced apoptosis in cancer cells. It is frequently downregulated, both at the mRNA and protein level, in hepatocellular carcinoma (HCC), but the mechanisms leading to this reduction are obscure...

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Identifiers

PMID: 23095110
DOI: 10.1089/omi.2012.0048

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23095110-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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