Article
Coevolution and hierarchical interactions of Tomato mosaic virus and the resistance gene Tm-1.
PLoS pathogens - 1 Jan 2012
Ishibashi Kazuhiro, Mawatari Natsuki, Miyashita Shuhei, Kishino Hirohisa, Meshi Tetsuo, Ishikawa Masayuki
Abstract excerpt
During antagonistic coevolution between viruses and their hosts, viruses have a major advantage by evolving more rapidly. Nevertheless, viruses and their hosts coexist and have coevolved, although the processes remain largely unknown. We previously identified Tm-1 that confers resistance to Tomato mosaic virus (ToMV), and revealed that it encodes a protein that binds ToMV replication proteins and inhibits RNA...
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