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Article

Structural basis for the recognition-evasion arms race between Tomato mosaic virus and the resistance gene Tm-1.

Proceedings of the National Academy of Sciences of the United States of America - 19 Aug 2014

Ishibashi Kazuhiro, Kezuka Yuichiro, Kobayashi Chihoko, Kato Masahiko, Inoue Tsuyoshi, Nonaka Takamasa, Ishikawa Masayuki, Matsumura Hiroyoshi, Katoh Etsuko

Abstract excerpt

The tomato mosaic virus (ToMV) resistance gene Tm-1 encodes a protein that shows no sequence homology to functionally characterized proteins. Tm-1 binds ToMV replication proteins and thereby inhibits replication complex formation. ToMV mutants that overcome this resistance have amino acid substitutions in the helicase domain of the replication proteins (ToMV-Hel). A small region of Tm-1 in the genome of the wild...

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PMID: 25092327
DOI: 10.1073/pnas.1407888111
PMCID: PMC4143053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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