Article
Gaining replicability in a nonhost compromises the silencing suppression activity of Tobacco mild green mosaic virus in a host.
Journal of virology - 1 Feb 2011
Ishibashi Kazuhiro, Meshi Tetsuo, Ishikawa Masayuki
Abstract excerpt
Natural isolates of Tobacco mild green mosaic virus (TMGMV) fail to infect tomato because the tomato tm-1 protein binds to the replication proteins of TMGMV and prevents RNA replication. Previously, we isolated a TMGMV mutant that overcomes tm-1-mediated resistance and multiplies in tomato plants. Here, we show that the causal mutations in the replication protein gene that abolish the interaction with tm-1 reduce...
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