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Article

Resistance breaking: integrated genomic and phenotypic insights into Orthotospovirus tomatomaculae strains overcoming Sw-5b and Tsw resistance.

BMC genomics - 28 Feb 2026

Chinnaiah Senthilraja, Netla Vamsidhar Reddy, Arora Arinder K, Srinivasan Rajagopalbabu, Gadhave Kiran R

Abstract excerpt

BACKGROUND: Tomato spotted wilt virus (TSWV) is a globally significant plant pathogen infecting more than 1,000 species and causing billion-dollar crop losses annually. The emergence of resistance-breaking (RB) strains has undermined single-gene resistance conferred by Sw-5b in tomato and Tsw in pepper, threatening durable resistance strategies. However, genomic and phenotypic characterization of novel RB strains...

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PMID: 41764465
DOI: 10.1186/s12864-026-12682-2
PMCID: PMC13059568

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