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Article

The effect of bradykinin B2 receptor polymorphisms on the susceptibility and severity of osteoarthritis in a Chinese cohort.

Journal of biomedicine & biotechnology - 1 Jan 2012

Chen Shuo, Zhou Yong, Li Jun, Shan Le-Qun, Fan Qing-Yu

Abstract excerpt

BACKGROUND: The B2-bradykinin receptor (BDKRB2) has been reported to associate with onset and development of Osteoarthritis (OA); however, the role of BDKRB2 genetic polymorphisms in OA remains unknown. METHOD: A total of 245 patients with primary knee OA and 264 healthy volunteer were recruited. BDKRB2 gene polymorphisms, -58T/C and +9/-9 bp polymorphisms, were genotyped. RESULTS: The genotype distributions and...

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Source

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Identifiers

PMID: 23093849
DOI: 10.1155/2012/597637
PMCID: PMC3470897

Genes

BDKRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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