Article
Analysis of EIF4G1 in Parkinson's disease among Asians.
Neurobiology of aging - 1 Apr 2013
Zhao Yi, Ho Patrick, Prakash Kumar-M, Foo Jia-Nee, Liu Jian-Jun, Au Wing-Lok, Tan Louis C, Tan Eng-King
Abstract excerpt
Sequence analysis of all the exons of EIF4G1 in 96 Asian patients with Parkinson's disease (PD) did not reveal any pathogenic mutations. A novel coding variant (Pro693Ser) in exon 15 (position 2077) was detected in one PD patient but not in 539 control subjects. Analysis of a coding polymorphic variant (rs2178403) in 1330 subjects revealed similar frequency between control subjects (0.638) and PD patients...
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