Article
The EIF4G1 gene and Parkinson's disease.
Acta neurologica Scandinavica - 1 Aug 2015
Deng H, Wu Y, Jankovic J
Abstract excerpt
Variants in the EIF4G1 gene have been recently identified to be responsible for autosomal dominant PD (PARK18), but its role in the PD-related neurodegeneration is unclear. Several EIF4G1 mutation/variants were found to be associated with PD, and functional studies have suggested that these variants may impair the ability of cells to rapidly and dynamically respond to stress, thus probably participating in the...
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