Article
HER2 Ile655Val and PTEN IVS4 polymorphisms in patients with breast cancer.
Molecular biology reports - 1 Feb 2013
Ozturk Oguz, Canbay Emel, Kahraman Ozlem T, Fatih Seyhan M, Aydogan Fatih, Celik Varol, Uras Cihan
Abstract excerpt
Although HER2/PTEN pathway is commonly disrupted in cancer, association of HER2 and PTEN polymorphisms with breast cancer (BC) remains controversial. We investigated the HER2 Ile655 Val and PTEN IVS4 polymorphisms in patients with BC in Turkish population. HER2 Ile655Val (rs 1136201) and PTEN IVS4 (rs 3830675) polymorphisms were determined using polymerase chain reaction-based restriction fragment length...
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