Article
Effect of Caenorhabditis elegans age and genotype on horizontal gene transfer in intestinal bacteria.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2013
Portal-Celhay Cynthia, Nehrke Keith, Blaser Martin J
Abstract excerpt
Horizontal gene transfer (HGT) between bacteria occurs in the intestinal tract of their animal hosts and facilitates both virulence and antibiotic resistance. A model in which both the pathogen and the host are genetically tractable facilitates developing insight into mechanistic processes enabling or restricting the transfer of antibiotic resistance genes. Here we develop an in vivo experimental system to study...
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