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Article

Genetic variation in gut microbe as a key regulator of host social behavior in C. elegans.

Gut microbes - 1 Dec 2025

Li Ying, Bai Ruijie, Zhu Yao, Shi Peng, Wang Tao, Zhou Dianshuang, Zhou Jianteng, Zhu Tao, Zhang Xinrong, Gu Rongrong, Ding Xiaoyue, Chen Hao, Wang Xiangming, Zhu Zuobin

Abstract excerpt

Gut microbiota have been shown to influence the social behaviors of their hosts, while variations in host genetics can affect the composition of the microbiome. Nonetheless, the degree to which genetic variations in microbial populations impact host behavior, as well as any potential transgenerational effects, remains inadequately understood. Utilizing C. elegans as a model organism, we identified 77 strains of...

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Identifiers

PMID: 40223740
DOI: 10.1080/19490976.2025.2490828
PMCID: PMC12005443

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