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Metabolic footprinting of mutant libraries to map metabolite utilization to genotype.

ACS chemical biology - 18 Jan 2013

Baran Richard, Bowen Benjamin P, Price Morgan N, Arkin Adam P, Deutschbauer Adam M, Northen Trent R

Abstract excerpt

The discrepancy between the pace of sequencing and functional characterization of genomes is a major challenge in understanding complex microbial metabolic processes and metabolic interactions in the environment. Here, we identified and validated genes related to the utilization of specific metabolites in bacteria by profiling metabolite utilization in libraries of mutant strains. Untargeted mass spectrometry...

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PMID: 23082955
DOI: 10.1021/cb300477w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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