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Article

Genome-wide association identifies multiple genomic regions associated with susceptibility to and control of ovine lentivirus.

PloS one - 1 Jan 2012

White Stephen N, Mousel Michelle R, Herrmann-Hoesing Lynn M, Reynolds James O, Leymaster Kreg A, Neibergs Holly L, Lewis Gregory S, Knowles Donald P

Abstract excerpt

BACKGROUND: Like human immunodeficiency virus (HIV), ovine lentivirus (OvLV) is macrophage-tropic and causes lifelong infection. OvLV infects one quarter of U.S. sheep and induces pneumonia and body condition wasting. There is no vaccine to prevent OvLV infection and no cost-effective treatment for infected animals. However, breed differences in prevalence and proviral concentration have indicated a genetic basis...

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Source

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Identifiers

PMID: 23082221
DOI: 10.1371/journal.pone.0047829
PMCID: PMC3474742

Genes

DLGAP1
SYTL3
DLG1
DPPA2
DPPA4
ZSCAN16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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