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Article

Systemic varicella zoster virus reactive effector memory T-cells impaired in the elderly and in kidney transplant recipients.

Journal of medical virology - 1 Dec 2012

van Besouw Nicole M, Verjans Georges M G M, Zuijderwijk Joke M, Litjens Nicolle H R, Osterhaus Albert D M E, Weimar Willem

Abstract excerpt

Varicella zoster virus (VZV) infections cause varicella and subsequently herpes zoster upon reactivation. Immune-compromised individuals and the elderly are at high risk of developing herpes zoster due to waning of VZV-specific T-cell immunity. In the present study, a novel functional T-cell assay was developed to test the correlation between age and VZV-specific T-cell responses in peripheral blood from healthy...

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Source

Identifiers

PMID: 23080511
DOI: 10.1002/jmv.23427

Genes

CCR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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