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Article

Influence of B cells in liver fibrosis associated with hepatitis B virus harboring basal core promoter mutations.

Journal of medical virology - 1 Dec 2012

Mohamadkhani Ashraf, Bastani Faegh, Sotoudeh Masoud, Sayehmiri Kourosh, Shahnazari Parisa, Montazeri Ghodratollah, Poustchi Hossein

Abstract excerpt

The development of the liver disease in chronic hepatitis B with common viral variants can be determined through the interaction between the virus and the host immune response. B cells constitute half of the intrahepatic lymphocyte population with an impact on fibrosis. A proliferation-inducing ligand (APRIL) has been shown to have a co-stimulatory activity on B cells. For this study HBV DNA was amplified and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23080492
DOI: 10.1002/jmv.23410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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