Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients.

PloS one - 1 Jan 2012

Pinto Pablo, Salgado Claudio Guedes, Santos Ney, Alencar Dayse O, Santos Sidney, Hutz Mara H, Ribeiro-dos-Santos Ândrea

Abstract excerpt

BACKGROUND: The CYP2E1 and GSTM1 genes encode metabolic enzymes that have key functions in drug modification and elimination. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the possible effects of CYP2E1 and GSTM1 polymorphisms in 71 leprosy patients and in 110 individuals from the general population. The GSTM1*0 null allele and INDEL CYP2E1*1D mutant genotypes were analyzed by conventional PCR, while CYP2E1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to Cytochrome P-450 CYP2E1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Glutathione Transferase

Share to Leprosy

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 23077626
DOI: 10.1371/journal.pone.0047498
PMCID: PMC3471857

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Polymorphisms in the CYP2E1 and GSTM1 genes as possible protection factors for leprosy patients.PMID 23077626Read ↗

A protective effect of glutathione-S-transferase GSTP1*Val(105) against polymorphic light eruption.Semantic proximity Read ↗

Association of Oral Submucous Fibrosis Risk with <em>GSTM1</em> and <em>GSTT1</em> Gene Polymorphisms.Semantic proximity Read ↗

Glutathione-S-transferase T1 genotyping and phenotyping in psoriasis patients receiving treatment with oral fumaric acid esters.Semantic proximity Read ↗

Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis.Semantic proximity Read ↗

Association of variants within the <i>GST</i> and other genes with anti-tubercular agents related toxicity: a systematic review and meta-analysisSemantic proximity Read ↗

Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a systematic review.Semantic proximity Read ↗

Polymorphisms of NAT2, CYP2E1, GST, and HLA related to drug-induced liver injury in indonesian tuberculosis patientsSemantic proximity Read ↗

Relationship of anti-tuberculosis drug-induced liver injury and genetic polymorphisms in CYP2E1 and GST.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.