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Article

Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis.

Bulletin of experimental biology and medicine - 1 Oct 2011

Kudryashov A V, Vavilin V A, Kolpakova T A, Mutaykhan Zh, Krasnov V A, Lyakhovich V V

Abstract excerpt

Association of CYP2E1 polymorphism with ALT activity increase was studied in patients with pulmonary tuberculosis receiving therapy by intermittent and daily protocols. The greatest increment of ALT activity in the group receiving therapy by intermittent protocol was seen in the patients with CYP2E1*7632TA genotype. In patients with wild homozygotic 1C/1C (6/6) genotype, ALT activity significantly increased, but...

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Share to Alanine Transaminase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2E1

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Share to Polymorphism, Genetic

Share to Tuberculosis, Pulmonary

Source

Identifiers

PMID: 22485222
DOI: 10.1007/s10517-011-1430-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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