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Article

Prion domain of yeast Ure2 protein adopts a completely disordered structure: a solid-support EPR study.

PloS one - 1 Jan 2012

Ngo Sam, Chiang Vicky, Ho Elaine, Le Linh, Guo Zhefeng

Abstract excerpt

Amyloid fibril formation is associated with a range of neurodegenerative diseases in humans, including Alzheimer's, Parkinson's, and prion diseases. In yeast, amyloid underlies several non-Mendelian phenotypes referred to as yeast prions. Mechanism of amyloid formation is critical for a complete understanding of the yeast prion phenomenon and human amyloid-related diseases. Ure2 protein is the basis of yeast...

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Identifiers

PMID: 23077577
DOI: 10.1371/journal.pone.0047248
PMCID: PMC3473064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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