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Article

Assembly of the yeast prion Ure2p into protein fibrils. Thermodynamic and kinetic characterization.

The Journal of biological chemistry - 8 Aug 2003

Fay Nicolas, Inoue Yuji, Bousset Luc, Taguchi Hideki, Melki Ronald

Abstract excerpt

The [URE3] phenotype in Saccharomyces cerevisiae propagates by a prion mechanism, involving the aggregation of the normally soluble and highly helical protein Ure2. Previous data have shown that the protein spontaneously forms in vitro long, straight, insoluble fibrils at neutral pH that are simi...

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Identifiers

PMID: 12777380
DOI: 10.1074/jbc.M303000200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12777380-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Assembly of the yeast prion Ure2p into protein fibrils. Thermodynamic and kinetic characterization.PMID 12777380Read ↗

Structural characterization of the fibrillar form of the yeast Saccharomyces cerevisiae prion Ure2p.Semantic proximity Read ↗

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