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Article

The insulin-like growth factor (IGF) signaling axis and hepatitis C virus-associated carcinogenesis (Review)

1 Jan 2012

Abstract excerpt

Insulin-like growth factor (IGF) signaling plays an important autocrine, paracrine and endocrine role in growth promotion involving various tissues and organs. Synthesis of both IGFs (IGF-1 and IGF-2) in normal conditions takes place mainly in the liver even if the proteins can be produced in every cell of the human body. The alterations in the IGF signaling axis in human hepatocarcinogenesis are described, but...

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Share to Growth Hormone and Insulin-like Growth Factors
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Identifiers

PMID: 23076735
DOI: 10.3892/ijo.2012.1666

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