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Article

A novel variation of GDF3 in Chinese Han children with a broad phenotypic spectrum of non-syndromic CHDs.

Cardiology in the young - 1 Oct 2015

Xiao Jianmin, Kang Guanyang, Wang Jing, Li Tengyan, Chen Jiuhao, Wang Jieyin, Li Wei, Wang Binbin

Abstract excerpt

BACKGROUND: The GDF3 gene plays a fundamental role in embryonic morphogenesis. Recent studies have indicated that GDF3 plays a previously unrecognised role in cardiovascular system development. Non-syndromic CHDs might be a clinically isolated manifestation of GDF3 mutations. The purpose of the present study was to identify potential pathological mutations in the GDF3 gene in Chinese children with non-syndromic...

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Identifiers

PMID: 25372014
DOI: 10.1017/S1047951114002170

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GDF3

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