Signal peptide-length variation in human apolipoprotein B gene. Molecular characteristics and association with plasma glucose levels.

doi:10.2337/diab.40.11.1539

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Article

Signal peptide-length variation in human apolipoprotein B gene. Molecular characteristics and association with plasma glucose levels.

Diabetes - 1 Nov 1991

Boerwinkle E, Chen S H, Visvikis S, Hanis C L, Siest G, Chan L

Abstract excerpt

We studied the molecular characteristics of three naturally occurring variants in the human apolipoprotein B (apoB) signal peptide, their frequencies in non-insulin-dependent diabetic and random populations, and their association with several measures of lipid and carbohydrate metabolism. In a random sample of 197 French whites, there were two common alleles, 5'beta SP-24 and 5'beta SP-27, with frequencies of...

Topics

Adult
Alleles
Amino Acid Sequence
Apolipoproteins B
Base Sequence
Blood Glucose
DNA
Diabetes Mellitus, Type 2
Female
Genetic Variation
Humans
Lipids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Molecular Sequence Data

Mutation

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 1936612
DOI: 10.2337/diab.40.11.1539

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1936612-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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