Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of two variants in the interleukin-6 receptor gene and premature coronary heart disease in a Chinese Han population.

Molecular biology reports - 1 Feb 2013

Chen Zhong, Qian Qi, Tang Chengchun, Ding Jiandong, Feng Yi, Ma Genshan

Abstract excerpt

Two novel single nucleotide polymorphisms (SNPs; rs7529229 and rs2228145) in the interleukin-6 receptor (IL6R) gene have recently been associated with coronary heart disease (CHD) in a European population. We sought to replicate this finding and to investigate associations of these two SNPs with the severity and clinical phenotypes of premature CHD in a Chinese Han population. A total of 418 patients were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Coronary Disease

Share to Gene Frequency

Share to Genetic Association Studies

Share to Polymorphism, Single Nucleotide

Share to Receptors, Interleukin-6

Source

Identifiers

PMID: 23073775
DOI: 10.1007/s11033-012-2143-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of two variants in the interleukin-6 receptor gene and premature coronary heart disease in a Chinese Han population.PMID 23073775Read ↗

An association study between genetic polymorphism in the interleukin-6 receptor gene and coronary heart disease.Semantic proximity Read ↗

A novel major histocompatibility complex locus confers the risk of premature coronary artery disease in a Chinese Han population.Semantic proximity Read ↗

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies.Semantic proximity Read ↗

Interleukin-6 receptor rs7529229 T/C polymorphism is associated with left main coronary artery disease phenotype in a Chinese population.Semantic proximity Read ↗

No association of interleukin-6 gene polymorphism (-174 G/C) with premature coronary artery disease in a Turkish cohort.Semantic proximity Read ↗

Study of Five Pubertal Transition-Related Gene Polymorphisms as Risk Factors for Premature Coronary Artery Disease in a Chinese Han Population.Semantic proximity Read ↗

IL-24 gene polymorphisms are associated with cardiometabolic parameters and cardiovascular risk factors but not with premature coronary artery disease: the genetics of atherosclerotic disease Mexican study.Semantic proximity Read ↗

Polymorphisms of -174G>C and -572G>C in the interleukin 6 (IL-6) gene and coronary heart disease risk: a meta-analysis of 27 research studies.Semantic proximity Read ↗

Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease--the Indian Atherosclerosis Research Study.Semantic proximity Read ↗

Sterol regulatory element-binding transcription factor (SREBF)-2, SREBF cleavage-activating protein (SCAP), and premature coronary artery disease in a Chinese population.Semantic proximity Read ↗

Interleukin-6 −174G>C Polymorphism and Risk of Coronary Heart Disease in West of Scotland Coronary Prevention Study (WOSCOPS)Semantic proximity Read ↗

Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.