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Article

Polymorphisms in the IL6 gene in Asian Indian families with premature coronary artery disease--the Indian Atherosclerosis Research Study.

Thrombosis and haemostasis - 1 May 2008

Maitra Arindam, Shanker Jayashree, Dash Debabrata, John Shibu, Sannappa Prathima R, Rao Veena S, Ramanna Jayakumar K, Kakkar Vijay V

Abstract excerpt

Inflammation plays a major role in coronary artery disease (CAD). We investigated the polymorphisms in the interleukin 6 (IL6) gene and their effect on the expression of acute-phase proteins in premature CAD in Asian Indian families. One hundred and ninety affected sibling pairs (ASPs) were genotyped for three tag single nucleotide polymorphisms (SNPs) in the IL6 gene for linkage analysis. We observed suggestive...

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PMID: 18449426
DOI: 10.1160/TH07-11-0686

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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