Article
Killer cell immunoglobulin like receptor gene association with tuberculosis.
Human immunology - 1 Jan 2013
Pydi Satya Sudheer, Sunder Sharada Ramaseri, Venkatasubramanian Sambasivan, Kovvali Srinivas, Jonnalagada Subbanna, Valluri Vijaya Lakshmi
Abstract excerpt
NK cells are vital components of innate immune system and are the first cells which come into picture mediating resistance against intracellular pathogens. NK cell cytotoxicity is modulated by a wide variety of cell surface receptors that recognize and respond towards infected cells. Activation of NK cells are controlled by both inhibitory and activating receptors, encoded by KIR genes and bind to HLA ligands....
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