Article
G-A variant in miR-200c binding site of EFNA1 alters susceptibility to gastric cancer.
Molecular carcinogenesis - 1 Mar 2014
Li Yingfei, Nie Yuqiang, Cao Jie, Tu Sanfang, Lin Yong, Du Yanlei, Li Yuyuan
Abstract excerpt
MicroRNAs (miRNAs) post-transcriptionally modulate gene expression by binding to complementary sites at 3'-untranslated regions (3'UTRs) of their target messenger RNAs (mRNAs). Genetic variations in miRNA binding sites may alter individual susceptibilities to many cancers. However, whether miRNA binding site single nucleotide polymorphisms (SNPs) interfere with gastric cancer (GC) susceptibility has not been...
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