Article
Influence of vascular endothelial growth factor single nucleotide polymorphisms on non-small cell lung cancer tumor angiogenesis.
Oncology reports - 1 Jan 2013
Maeda Ai, Nakata Masao, Yasuda Koichiro, Yukawa Takuro, Saisho Shinsuke, Okita Riki, Hirami Yuji, Shimizu Katsuhiko
Abstract excerpt
Vascular endothelial growth factor (VEGF) plays an important role in tumor angiogenesis. Several studies have reported that genomic VEGF polymorphisms may influence VEGF synthesis. To evaluate the role of VEGF single nucleotide polymorphisms (SNPs), we examined the expression of several angiogenesis-related proteins [VEGF, hypoxia-inducible factor-1α (HIF-1α) and...
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