Article
Polymorphism of VEGF-460C/T associated with the risk and clinical characteristics of lung cancer in Chinese population.
Medical oncology (Northwood, London, England) - 1 Mar 2013
Sun Shi-Fang, Huang Da-Bing, Cao Chao, Deng Zai-Chun
Abstract excerpt
Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis in the process of tumor growth and metastasis. Different VEGF gene polymorphisms have been shown to result in different VEGF protein expression in cancer cells and tumor angiogenic activity. We conducted a case-control study to evaluate the genetic effects of VEGF-460C/T polymorphism on the development of lung cancer. One hundred and...
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