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Article

SMN is required for sensory-motor circuit function in Drosophila.

Cell - 12 Oct 2012

Imlach Wendy L, Beck Erin S, Choi Ben Jiwon, Lotti Francesco, Pellizzoni Livio, McCabe Brian D

Abstract excerpt

Spinal muscular atrophy (SMA) is a lethal human disease characterized by motor neuron dysfunction and muscle deterioration due to depletion of the ubiquitous survival motor neuron (SMN) protein. Drosophila SMN mutants have reduced muscle size and defective locomotion, motor rhythm, and motor neuron neurotransmission. Unexpectedly, restoration of SMN in either muscles or motor neurons did not alter these...

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Identifiers

PMID: 23063130
DOI: 10.1016/j.cell.2012.09.011
PMCID: PMC3475188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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