Article
Clinical outcomes of thoracic radiotherapy for locally advanced NSCLC with EGFR mutations or EML4-ALK rearrangement.
Anticancer research - 1 Oct 2012
Hayashi Hidetoshi, Okamoto Isamu, Kimura Hideharu, Sakai Kazuko, Nishimura Yasumasa, Nishio Kazuto, Nakagawa Kazuhiko
Abstract excerpt
BACKGROUND: Little is known about the occurrence and consequences of epidermal growth factor receptor gene (EGFR) mutations and the fusion of the echinoderm microtubule-associated protein-like 4 (EML4) and anaplastic lymphoma kinase (ALK) genes in locally advanced non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: We retrospectively examined 37 patients with locally advanced NSCLC treated with definitive...
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