Article
Association of BLCA-4 hypomethylation in blood leukocyte DNA and the risk of bladder cancer in a Chinese population.
Pathology oncology research : POR - 1 Apr 2013
Ji Hui-Xiang, Zhao Qian, Pan Jin-Hong, Shen Wen-Hao, Chen Zhi-Wen, Zhou Zhan-Song
Abstract excerpt
Global DNA hypomethylation has been associated with increased risk for cancers of the colorectum, bladder, breast, head and neck, and testicular germ cells. The aim of this study was to examine whether global hypomethylation measured at BLCA-4 repeat regions through bisulfite pyrosequencing in blood leukocyte DNA is associated with the risk of bladder cancer(BC). A total of 312 bladder cancer patients and 361...
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