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Detection of Bladder Cancer Using Novel DNA Methylation Biomarkers in Urine Sediments

1 Jul 2011

Abstract excerpt

BACKGROUND: Bladder cancer (BCa) remains a lethal malignancy that can be cured if detected early. DNA hypermethylation is a common epigenetic abnormality in cancer that may serve as a marker of disease activity. METHODS: We selected 10 novel candidate genes from the most frequently hypermethylated genes detected by DNA microarray and bisulfite pyrosequencing of bladder cancers and applied them to detect bladder...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 21586619
DOI: 10.1158/1055-9965.epi-11-0067

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