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Identification and validation of methylated PENK gene for early detection of bladder cancer using urine DNA

19 Nov 2022

Abstract excerpt

BACKGROUND: Early detection of bladder cancer (BCa) offers patients a favorable outcome and avoids the need for cystectomy. Development of an accurate and sensitive noninvasive BCa diagnostic test is imperative. DNA methylation is an early epigenetic event in the development of BCa. Certain specific aberrant methylations could serve as useful biomarkers. The aim of this study was to identify methylation...

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Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Urinary and Genital Oncology Studies

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PMID: 36403035
DOI: 10.1186/s12885-022-10275-2

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