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Anti-melanogenic activity of Myristica fragrans extract against Aspergillus fumigatus using phenotypic based screening

2 Mar 2020

Abstract excerpt

BACKGROUND: Aspergillus fumigatus, an opportunistic fungal pathogen is associated with a wide array of diseases. It produces 1, 8-dihydroxy naphthalene (DHN) melanin that imparts greenish grey color to conidia and is an important virulence factor. It masks various molecular patterns associated with A. fumigatus and protects the fungus from host immune system. Myristica fragrans, enriched with secondary...

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PMID: 32122336
DOI: 10.1186/s12906-020-2859-z

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