Two newly identified genetic determinants of pigmentation in Europeans.

doi:10.1038/ng.160

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Article

Two newly identified genetic determinants of pigmentation in Europeans.

Nature genetics - 1 Jul 2008

Sulem Patrick, Gudbjartsson Daniel F, Stacey Simon N, Helgason Agnar, Rafnar Thorunn, Jakobsdottir Margret, Steinberg Stacy, Gudjonsson Sigurjon A, Palsson Arnar, Thorleifsson Gudmar, Pálsson Snaebjörn, Sigurgeirsson Bardur, Thorisdottir Kristin, Ragnarsson Rafn, Benediktsdottir Kristrun R, Aben Katja K, Vermeulen Sita H, Goldstein Alisa M, Tucker Margaret A, Kiemeney Lambertus A, Olafsson Jon H, Gulcher Jeffrey, Kong Augustine, Thorsteinsdottir Unnur, Stefansson Kari

Abstract excerpt

We present results from a genome-wide association study for variants associated with human pigmentation characteristics among 5,130 Icelanders, with follow-up analyses in 2,116 Icelanders and 1,214 Dutch individuals. Two coding variants in TPCN2 are associated with hair color, and a variant at the ASIP locus shows strong association with skin sensitivity to sun, freckling and red hair, phenotypic characteristics...

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PMID: 18488028
DOI: 10.1038/ng.160

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ASIP
TPCN2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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