Article
Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up.
Human genetics - 1 Aug 2015
Liu Fan, Visser Mijke, Duffy David L, Hysi Pirro G, Jacobs Leonie C, Lao Oscar, Zhong Kaiyin, Walsh Susan, Chaitanya Lakshmi, Wollstein Andreas, Zhu Gu, Montgomery Grant W, Henders Anjali K, Mangino Massimo, Glass Daniel, Bataille Veronique, Sturm Richard A, Rivadeneira Fernando, Hofman Albert, van IJcken Wilfred F J, Uitterlinden André G, Palstra Robert-Jan T S, Spector Timothy D, Martin Nicholas G, Nijsten Tamar E C, Kayser Manfred
Abstract excerpt
In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of discovered loci. Our GWAS provide the first genome-wide significant evidence for chromosome 20q11.22 harboring the ASIP gene being explicitly associated with skin color in...
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