Article
Association between the IVS4G>T mutation in the TCF7L2 gene and susceptibility to diabetes in cystic fibrosis patients.
BMC research notes - 10 Oct 2012
Furgeri Daniela Tenório, Marson Fernando Augusto de Lima, Ribeiro Antonio Fernando, Bertuzzo Carmen Silvia
Abstract excerpt
BACKGROUND: Clinical complications appear to be a decisive factor for the prognosis of patients. Diabetes is an important complication of cystic fibrosis(CF). In our study we evaluated the association between the IVS4G>T mutation in the TCF7L2 gene with the presence of diabetes in patients with CF. FINDINGS: We evaluated 145 patients with CF in relation to the genotype of the IVS4G>T mutation. For this, the PCR...
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