Article
No association between the deltaF508 cystic fibrosis mutation and type 2 diabetes mellitus.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 1999
Braun J, Arnemann J, Lohrey M, Donner H, Siegmund T, Usadel K H, Badenhoop K
Abstract excerpt
Cystic fibrosis (CF) is one of the most common recessively inherited disorders in Caucasian populations and is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. A three base deletion known as deltaF508 occurs on about 70%, of CF chromosomes and accounts for the high prevalence of the disease. Since type 2 diabetes mellitus occurs more frequently in relatives of patients with CF than...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.