Genotype analysis in cystic fibrosis in relation to the occurrence of diabetes mellitus.

doi:10.1111/j.1399-0004.1993.tb04445.x

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Article

Genotype analysis in cystic fibrosis in relation to the occurrence of diabetes mellitus.

Clinical genetics - 1 Apr 1993

Hamdi I, Payne S J, Barton D E, McMahon R, Green M, Shneerson J M, Hales C N

Abstract excerpt

Carbohydrate intolerance and frank diabetes mellitus (DM) are recognised features of cystic fibrosis (CF), but their cause has not been established. Damage to the islet cells due to pancreatic fibrosis is the most common explanation. The relationship between the genotype and the occurrence of dia...

Topics

Adolescent
Adult
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Diabetes Mellitus
Female
Gene Frequency
Genotype
Glucose Tolerance Test
Humans
Male
Membrane Proteins
Mutation

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