Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Respiratory pathogens adopt a chronic lifestyle in response to bile.

PloS one - 1 Jan 2012

Reen F Jerry, Woods David F, Mooij Marlies J, Adams Claire, O'Gara Fergal

Abstract excerpt

Chronic respiratory infections are a major cause of morbidity and mortality, most particularly in Cystic Fibrosis (CF) patients. The recent finding that gastro-esophageal reflux (GER) frequently occurs in CF patients led us to investigate the impact of bile on the behaviour of Pseudomonas aeruginosa and other CF-associated respiratory pathogens. Bile increased biofilm formation, Type Six Secretion, and quorum...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile
Share to Biofilms
Share to Burkholderia cepacia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, Thin Layer

Share to Gastroesophageal Reflux

Share to Quinones

Share to Quorum Sensing

Share to Respiratory Tract Infections

Source

Open in PubMed Open full text

Identifiers

PMID: 23049911
DOI: 10.1371/journal.pone.0045978
PMCID: PMC3458808

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Respiratory pathogens adopt a chronic lifestyle in response to bile.PMID 23049911Read ↗

The interaction between bacteria and bileSemantic proximity Read ↗

Survival of the Fittest: How Bacterial Pathogens Utilize Bile To Enhance InfectionSemantic proximity Read ↗

Bifidobacterial biofilm formation is a multifactorial adaptive phenomenon in response to bile exposure.Semantic proximity Read ↗

Pulmonary Pathogens Adapt to Immune Signaling Metabolites in the AirwaySemantic proximity Read ↗

The Role of Bacterial Secretion Systems in the Virulence of Gram-Negative Airway Pathogens Associated with Cystic FibrosisSemantic proximity Read ↗

Interplay between biofilm microenvironment and pathogenicity of Pseudomonas aeruginosa in cystic fibrosis lung chronic infectionSemantic proximity Read ↗

Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyleSemantic proximity Read ↗

BILE ACIDS IN LOWER AIRWAYS AS A NOVEL INDICATOR OF AIRWAY MICROBIOTA CHANGES IN CHRONIC OBSTRUCTIVE PULMONARY DISEASESemantic proximity Read ↗

The role of multispecies social interactions in shaping Pseudomonas aeruginosa pathogenicity in the cystic fibrosis lungSemantic proximity Read ↗

Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts.Semantic proximity Read ↗

Airway commensal bacteria in cystic fibrosis inhibit the growth of P. aeruginosa via a released metaboliteSemantic proximity Read ↗

Lung infections associated with cystic fibrosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.