Article
Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts.
Infection and immunity - 1 Jun 2017
Nickerson Kourtney P, Chanin Rachael B, Sistrunk Jeticia R, Rasko David A, Fink Peter J, Barry Eileen M, Nataro James P, Faherty Christina S
Abstract excerpt
The Shigella species cause millions of cases of watery or bloody diarrhea each year, mostly in children in developing countries. While many aspects of Shigella colonic cell invasion are known, crucial gaps in knowledge regarding how the bacteria survive, transit, and regulate gene expression prior to infection remain. In this study, we define mechanisms of resistance to bile salts and build on previous research...
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