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Folic acid supplementation in pregnancy: are there devils in the detail?

9 Oct 2012

Abstract excerpt

Maternal folic acid (FA) supplementation is well recognised to protect against neural tube defects. Folate is a critical cofactor in one-carbon metabolism involved in the epigenetic regulation of transcription that underpins development. Thus, it is possible that maternal FA supplementation may have additional, unforeseen persistent effects in the offspring. This is supported by the modification by maternal...

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PMID: 23046900
DOI: 10.1017/s0007114512003765

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