Article
Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease.
Annual review of nutrition - 21 Aug 2010
Burdge Graham C, Lillycrop Karen A
Abstract excerpt
There is considerable evidence for induction of differential risk of noncommunicable diseases in humans by variation in the quality of the early life environment. Studies in animal models show that induction and stability of induced changes in the phenotype of the offspring involve altered epigenetic regulation by DNA methylation and covalent modifications of histones. These findings indicate that such epigenetic...
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